Original Article

• Immunomodulatory and Antiviral Therapy Improved Functional Cure Rate in CHB Patients with High HBsAg Level Experienced NA

  Hongyu Jia, Guodong Yu, Jiong Yu, Xiaoli Zhang, Lisha Yang, Bin Wang, Jiming Zhang, Lang Bai, Xinxin Zhang, Kai Wang, Ping Zhao, Dongliang Yang, Yingren Zhao, Yanyan Yu, Yimin Zhang, Jueqing Gu, Chanyuan Ye, Huan Cai, Yingfeng Lu, Dairong Xiang, Liang Yu, Jiangshan Lian, Jianhua Hu, Shanyan Zhang, Ciliang Jin, Yida Yang

  
• Functional Cure of Chronic Hepatitis B with Antiviral Treatment in Children Having High-level Viremia and Normal or Mildly Elevated Serum Aminotransferase

  Jing Li, Peiyao Fan, Zhiqiang Xu, Yi Dong, Fuchuan Wang, Weiguo Hong, Jinfang Zhao, Yinjie Gao, Jianguo Yan, Lili Cao, Chao Zhang, Shishu Zhu, Fu-Sheng Wang, Min Zhang

  
• High Frequency of Antiviral Resistance Mutations in HBV Genotypes A2 and H: Multidrug Resistance Strains in Mexico

  Alexis Jose-Abrego, Sonia Roman, João Renato Rebello Pinho, Michele Soares Gomes-Gouvêa, Arturo Panduro

  

• Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease

  Jian-Bin Zhang, Meng-Ting Li, Shuang-Zhe Lin, Yu-Qing Cheng, Jian-Gao Fan, Yuan-Wen Chen

  
• High-intensity Interval Training for the Management of Nonalcoholic Steatohepatitis: Participant Experiences and Perspectives

  Shelley E. Keating, Ilaria Croci, Matthew P. Wallen, Emily R. Cox, Jeff S. Coombes, Nicola W. Burton, Graeme A. Macdonald, Ingrid J. Hickman

  
• Community-centered Disease Severity Assessment of Metabolic Dysfunction-associated Fatty Liver Disease

  Jee-Fu Huang, Pei-Chien Tsai, Ming-Lun Yeh, Chung-Feng Huang, Ching-I Huang, Mei-Hsuan Lee, Po-Yau Hsu, Chih-Wen Wang, Yu-Ju Wei, Po-Cheng Liang, Yi-Hung Lin, Meng-Hsuan Hsieh, Jeng-Fu Yang, Ming-Yen Hsieh, Tyng-Yuan Jang, Ming-Jong Bair, Zu-Yau Lin, Chia-Yen Dai, Ming-Lung Yu, Wan-Long Chuang

  

• Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis

  Lu Zhang, Mingfu Wang, Ran An, Jun Dai, Shujun Liu, Ming Chen, Haoran Ding

  
• IL-33 Downregulates Hepatic Carboxylesterase 1 in Acute Liver Injury via Macrophage-derived Exosomal miR-27b-3p

  Ping Gao, Min Li, Jingli Lu, Daochun Xiang, Ximin Wang, Yanjiao Xu, Yue Zu, Xinlei Guan, Guodong Li, Chengliang Zhang

  
• Histopathological Features Predicting Long-term Clinical Outcomes in Patients with Vanishing Bile Duct Syndrome

  Tingting Lv, Haitian Yu, Xiao Han, Aileen Wee, Jimin Liu, Min Li, Jinghang Xu, Xiaoli Hu, Jia Li, Weijia Duan, Tailing Wang, Jidong Jia, Xinyan Zhao

  

• Exosome-transported circHDAC1_004 Promotes Proliferation, Migration, and Angiogenesis of Hepatocellular Carcinoma by the miR-361-3p/NACC1 Axis

  Bin Xu, Wenbo Jia, Yanzhi Feng, Jinyi Wang, Jing Wang, Deming Zhu, Chao Xu, Litao Liang, Wenzhou Ding, Yongping Zhou, Lianbao Kong

  
• Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma

  Keren Li, Yi Niu, Kai Li, Chengrui Zhong, Zhiyu Qiu, Yichuan Yuan, Yunxing Shi, Zhu Lin, Zhenkun Huang, Dinglan Zuo, Yunfei Yuan, Binkui Li

  
• Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma: Real-life Data on Liver Disease, Treatment and Prognosis

  Xavier Adhoute, Olivia Pietri, Guillaume Pénaranda, Thomas Wolf, Patrick Beaurain, Olivier Monnet, Arthur Laquière, Justine Bonomini, Frédéric Neumann, Olivier Levrel, Jean-Pascal Buono, Xavier Hanna, Paul Castellani, Hervé Perrier, Marc Bourliere, Rodolphe Anty

  
• CENPA-driven STMN1 Transcription Inhibits Ferroptosis in Hepatocellular Carcinoma

  Daomiao Liang, Lanzhu Luo, Jiang Wang, Tongyu Liu, Chao Guo

  

• Carvedilol Versus Other Nonselective Beta Blockers for Variceal Bleeding Prophylaxis and Death: A Network Meta-analysis

  Ka-Shing Cheung, Chiu-Hang Mok, Lok-Ka Lam, Xian-Hua Mao, Lung-Yi Mak, Wai-Kay Seto, Man-Fung Yuen

  
• Serum Soluble Vascular Endothelial Growth Factor Receptor 1 as a Potential Biomarker of Hepatopulmonary Syndrome

  Yu-Jie Li, Xian-Feng Wu, Dan-Dan Wang, Peng Li, Hao Liang, Xiao-Yan Hu, Jia-Qi Gan, Yi-Zhu Sun, Jun-Hong Li, Jun Li, Xin Shu, Ai-Lin Song, Chun-Yong Yang, Zhi-Yong Yang, Wei-Feng Yu, Li-Qun Yang, Xiao-Bo Wang, Karine Belguise, Zheng-Yuan Xia, Bin Yi

  

Review Article

• Roles and Molecular Mechanisms of Biomarkers in Hepatocellular Carcinoma with Microvascular Invasion: A Review   

  Xudong Zhao, Yudan Wang, Haoming Xia, Shuqiang Liu, Ziyue Huang, Risheng He, Liang Yu, Nanfeng Meng, Hang Wang, Junqi You, Jinglin Li, Judy Wai Ping Yam, Yi Xu, Yunfu Cui

  
• Current Status and Analysis of Machine Learning in Hepatocellular Carcinoma   

  Sijia Feng, Jianhua Wang, Liheng Wang, Qixuan Qiu, Dongdong Chen, Huo Su, Xiaoli Li, Yao Xiao, Chiayen Lin

  
• Diagnostic and Prognostic Value of Protein Post-translational Modifications in Hepatocellular Carcinoma   

  Jing Wang, Fangfang Wang, Ning Wang, Mei-Yin Zhang, Hui-Yun Wang, Guo-Liang Huang

  
• Portal Hypertension in Nonalcoholic Fatty Liver Disease: Challenges and Paradigms   

  Emilie K. Mitten, Piero Portincasa, György Baffy

  
• Liver Fat Scores for Noninvasive Diagnosis and Monitoring of Nonalcoholic Fatty Liver Disease in Epidemiological and Clinical Studies   

  Mona Reinshagen, Stefan Kabisch, Andreas F.H. Pfeiffer, Joachim Spranger

  
• Noninvasive Fibrosis Assessment in Chronic Hepatitis C Infection: An Update   

  Kristina Bojanic, Mirta Sudaric Bogojevic, Sonja Vukadin, Renata Sikora, Gordana Ivanac, Nikola Raguz Lucic, Martina Smolic, Ashraf A. Tabll, George Y. Wu, Robert Smolic

  
• Epidemiology and Management of Drug-induced Liver Injury: Importance of the Updated RUCAM   

  Takashi Kobayashi, Michihiro Iwaki, Asako Nogami, Masato Yoneda

  
• Emerging Evidence Linking the Liver to the Cardiovascular System: Liver-derived Secretory Factors   

  Xiang Liu, Yijia Shao, Linjiang Han, Ruyue Zhang, Jimei Chen

  
• Hepatitis Virus-associated Non-hodgkin Lymphoma: Pathogenesis and Treatment Strategies   

  Wenjing Zhang, Fan Du, Li Wang, Tao Bai, Xiang Zhou, Heng Mei

  
• Current Therapeutics in Primary Sclerosing Cholangitis   

  Natassia Tan, John Lubel, William Kemp, Stuart Roberts, Ammar Majeed

  

Research Letter

• Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease   

  Artemiy Kovynev, Zhixiong Ying, Joost M. Lambooij, Hendrik J.P. van der Zande, Bruno Guigas, Patrick C.N. Rensen, Milena Schönke

  

Corrigendum

• Corrigendum: RP11-40C6.2 Inactivates Hippo Signaling by Attenuating YAP1 Ubiquitylation in Hepatitis B Virus-associated Hepatocellular Carcinoma