Keywords: Toxicity; Efficacy; Chinese Medicine; Omics; Network Pharmacology; Network Toxicology; Bioinformatics
Having multiple components, multiple effects and multiple targets and containing multiple active ingredients are important characteristics influencing the efficacy and toxicity of traditional Chinese medicine (TCM). Also, the scientific connotation and mutual relationships between the toxicity and efficacy of TCM are of worldwide interest. Recently, based on the application of some innovative strategies and methods, including omics technologies (e.g., genomics, transcriptomics, proteomics, and metabolomics), network pharmacology, network toxicology, and bioinformatics, great progress has been made in understanding the efficacy, toxicity, and mechanisms of action and material basis of TCM.
This issue welcomes basic and translational reports on the efficacy, toxicity, and material basis of effective ingredients, single herbs and compounds of TCM. Publications in this issue aim not only to collect the emerging studies about the efficacy and toxicity of TCM but also to determine how this information might be used to discover novel herbal drugs and develop better therapeutic strategies.