Original Article

Integrated Analysis of Serum and Fecal Metabolites Reveals the Role of Bile Acid Metabolism in Drug-induced Liver Injury: Implications for Diagnostic and Prognostic Biomarkers Simiao Yu, Sici Wang, Ping Li, Haocheng Zheng, Jing Jing, Tingting He, Xia Ding, Ruilin Wang Published online: June 30, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00073

Interim Analysis of 48-week Tenofovir Amibufenamide Treatment in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase Levels: The PROMOTE Study Honglian Gui, Yingqiu Shen, Lin Tan, Piao Hu, Feng Qian, Xiaoping Wu, Yuanwang Qiu, Sujun Zheng, Jiaojian Lv, Yunzhen Shi, Jun Li, Yongfang Jiang, Zhizhen Hu, Fanru Nie, Yan Huo, Lihong Qu, Qing Xie Published online: June 30, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00162

Global Trends and Cross-country Inequalities of Acute Hepatitis E in the Elderly, 1990–2021: A Comprehensive Analysis Deliang Huang, Jinyan Jiang, Jinghan Peng, Zhibin Zhu, Yuanyuan Chen, Siyu Zhang, Huiyi Lai, Hong Yu, Qi Zhao, Yanna Wu, Yanping Chen, Jun Chen Published online: May 30, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00101

The Gut Microbiota in Elderly Patients with Acute Hepatitis E Infection Miaomiao Li, Meng Shi, Changyi Ji, Luyu Wang, Ze Xiang, Ying Wang, Hongtao Wang, Mengmeng Gu, Runing Ji, Jian Wu Published online: May 26, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00111

Adrenomedullin as an Immunomodulator of CD14+MerTK+ Circulating Monocytes in Liver Failure Syndromes Francesca Maria Trovato, Florent Artru, Roosey Sheth, Rima Abdalla, Joseph Wilson, Anna Broderick, John Smith, Stephen Atkinson, Mark J. McPhail Published online: June 24, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00074

Assessment of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Cross-sectional Study in Asymptomatic Individuals in Greater Vancouver Nicholas W. Tjandra, David M.P. Di Fonzo, Tianyi Wen, Kirby Lau, Peter Kwan, Eric M. Yoshida, Daljeet Chahal Published online: June 23, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00109

Short-term Physical Activity Reduces Metabolic-associated Steatohepatitis by Promoting the Degradation of Branched-chain Amino Acids in Skeletal Muscle Mingshu Gao, Jiaying Li, Yanan Zhang, Jiangtao Huang, Jiaqi Chen, Dawen Liao, Shengnan He, Qian Bi, Lele Ji, Yulu Du Published online: May 30, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00072

CCNE1 Promotes the Progression of Hepatic Precancerous Lesion and the Malignant Phenotype of Hepatocellular Carcinoma Kai Zhang, Xue Hu, Lichao Yao, Wenzhi Guo Published online: April 28, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00428

Review Article

Orphan Nuclear Receptors in Metabolic Dysfunction-associated Steatotic Liver Disease Development Huan Li, Jian Chen, Ziyin Huang, Mingkai Chen Published online: June 19, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00019

Epidemiology, Achievements, and Challenges in the Elimination of Hepatitis B in China You Deng, Tongtong Meng, Hong You, Jidong Jia, Yu Wang Published online: May 21, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00039

Research Letter

Complete Resolution of Refractory Ascites and Pleural Effusion with Sustained Improvement in Urinary Sodium Excretion in a Cirrhotic Patient Treated with Empagliflozin Wei Qin, Yunyi Gao, Yuanyuan Zhao, Ning Bian, Weiguang Fan, Wei Wang, Yuan Gao, Zhongjie Hu Published online: June 19, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00172

Characteristics of a Chinese Cohort of Patients with Chronic Hepatitis C Infection (2019–2023) and a Case Report of Resistance-associated Substitutions to Sofosbuvir-velpatasvir Treatment Hao Xiong, Shaokun Pan, Chaohui Zhou, Hong Shi, Youhua Xie, Jinsheng Guo Published online: April 10, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00033

Letter to the Editor

Anti-mitochondrial Antibodies in Patients with Elevated Alkaline Phosphatase/Gamma-glutamyl Transferase Levels: Hallmark or Bystander? Fukui Zhang Published online: June 30, 2025 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00168