Original Article

• Integrated Analysis of Serum and Fecal Metabolites Reveals the Role of Bile Acid Metabolism in Drug-induced Liver Injury: Implications for Diagnostic and Prognostic Biomarkers

  Simiao Yu, Sici Wang, Ping Li, Haocheng Zheng, Jing Jing, Tingting He, Xia Ding, Ruilin Wang

  

• Interim Analysis of 48-week Tenofovir Amibufenamide Treatment in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase Levels: The PROMOTE Study

  Honglian Gui, Yingqiu Shen, Lin Tan, Piao Hu, Feng Qian, Xiaoping Wu, Yuanwang Qiu, Sujun Zheng, Jiaojian Lv, Yunzhen Shi, Jun Li, Yongfang Jiang, Zhizhen Hu, Fanru Nie, Yan Huo, Lihong Qu, Qing Xie

  
• Global Trends and Cross-country Inequalities of Acute Hepatitis E in the Elderly, 1990–2021: A Comprehensive Analysis

  Deliang Huang, Jinyan Jiang, Jinghan Peng, Zhibin Zhu, Yuanyuan Chen, Siyu Zhang, Huiyi Lai, Hong Yu, Qi Zhao, Yanna Wu, Yanping Chen, Jun Chen

  
• The Gut Microbiota in Elderly Patients with Acute Hepatitis E Infection

  Miaomiao Li, Meng Shi, Changyi Ji, Luyu Wang, Ze Xiang, Ying Wang, Hongtao Wang, Mengmeng Gu, Runing Ji, Jian Wu

  

• Adrenomedullin as an Immunomodulator of CD14⁺MerTK⁺ Circulating Monocytes in Liver Failure Syndromes

  Francesca Maria Trovato, Florent Artru, Roosey Sheth, Rima Abdalla, Joseph Wilson, Anna Broderick, John Smith, Stephen Atkinson, Mark J. McPhail

  

• Assessment of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Cross-sectional Study in Asymptomatic Individuals in Greater Vancouver

  Nicholas W. Tjandra, David M.P. Di Fonzo, Tianyi Wen, Kirby Lau, Peter Kwan, Eric M. Yoshida, Daljeet Chahal

  
• Short-term Physical Activity Reduces Metabolic-associated Steatohepatitis by Promoting the Degradation of Branched-chain Amino Acids in Skeletal Muscle

  Mingshu Gao, Jiaying Li, Yanan Zhang, Jiangtao Huang, Jiaqi Chen, Dawen Liao, Shengnan He, Qian Bi, Lele Ji, Yulu Du

  

• CCNE1 Promotes the Progression of Hepatic Precancerous Lesion and the Malignant Phenotype of Hepatocellular Carcinoma

  Kai Zhang, Xue Hu, Lichao Yao, Wenzhi Guo

  

Review Article

• Orphan Nuclear Receptors in Metabolic Dysfunction-associated Steatotic Liver Disease Development

  Huan Li, Jian Chen, Ziyin Huang, Mingkai Chen

  
• Epidemiology, Achievements, and Challenges in the Elimination of Hepatitis B in China

  You Deng, Tongtong Meng, Hong You, Jidong Jia, Yu Wang

  

Research Letter

• Complete Resolution of Refractory Ascites and Pleural Effusion with Sustained Improvement in Urinary Sodium Excretion in a Cirrhotic Patient Treated with Empagliflozin

  Wei Qin, Yunyi Gao, Yuanyuan Zhao, Ning Bian, Weiguang Fan, Wei Wang, Yuan Gao, Zhongjie Hu

  
• Characteristics of a Chinese Cohort of Patients with Chronic Hepatitis C Infection (2019–2023) and a Case Report of Resistance-associated Substitutions to Sofosbuvir-velpatasvir Treatment

  Hao Xiong, Shaokun Pan, Chaohui Zhou, Hong Shi, Youhua Xie, Jinsheng Guo

  

Letter to the Editor

• Anti-mitochondrial Antibodies in Patients with Elevated Alkaline Phosphatase/Gamma-glutamyl Transferase Levels: Hallmark or Bystander?

  Fukui Zhang