Original Article

• A Novel Simplified Prognostic Model for 90-day Transplant-free Survival in Patients with Severe Acute Liver Injury/Acute Liver Failure

  Yan Ren, Manman Xu, Wenling Wang, Ming Kong, Yu Chen

  

• Bile Drainage Improves Survival in Amatoxin-induced Severe Liver Injury: A Prospective Pilot Cohort Study

  Xiuying Ma, Bin Han, Wei Yue, Yuan Shen, Jiawei Geng

  
• A Multi-omics and Machine Learning Framework Identifies Plasma SBDS as a Causal Biomarker and Therapeutic Target in Primary Sclerosing Cholangitis

  Pengfei Cheng, Yuanming Qiang, Yibo Sun, Binwei Duan, Yabo Ouyang, Guangming Li

  

Review Article

• Short-chain Fatty Acids and Bile Acids Signaling in Chronic Hepatitis B

  Siqi Sun, Sisi Yang, Yihe Yu, Jiyang Chen, Jintao Ning, Yida Yang, Hongyu Jia

  
• The Association of Alpha-1 Antitrypsin Deficiency and Arterial Aneurysms: An Update and Review

  Moana Da Silva Santiago, George Y. Wu

  
• The Multifaceted Roles of Gut Microbiota and Their Metabolites in Metabolic Dysfunction-associated Steatotic Liver Disease: A Literature Review

  Yunqi Zhang, Dengqin Wang, Bo Zhuang, Fangzhuo Zhu, Chengwei Tan, Jing Zhang, Qianqian Zhang

  
• Dubin-Johnson and Rotor Syndromes: A Review and Update of Pathophysiological Mechanisms

  Bianca Thakkar, George Y. Wu

  
• Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure

  Hong Zhou, Hong Wu, Shao-Hui Su, Shan-Hong Tang

  

Letter to the Editor

• Letter to the Editor: Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study

  Chenhao Ye, Lei Wang