Original Article

• TF-rs1049296 C>T Variant Modifies the Association between Hepatic Iron Stores and Liver Fibrosis in Metabolic Dysfunction-associated Steatotic Liver Disease

  Sui-Dan Chen, Ka-Te Huang, Huai Zhang, Yang-Yang Li, Yi Jin, Hai-Yang Yuan, Pei-Wu Zhu, Jian-Min Li, Christopher D. Byrne, Giovanni Targher, Ming-Hua Zheng

  
• Oxytocin Attenuates Metabolic Dysfunction-associated Steatotic Liver Disease via AMPK/SREBP1c/FAS-mediated Suppression of Hepatic Lipogenesis

  Yue Xu, Siqian Lu, Hongpei Wu, Haifeng Wu, Ming Li, Meng Zhou, Ting Chen, Xun Wang, Lishuai Qu, Qin Jin, Jinxia Liu

  

• Prognostic Nutritional Index Predicts Outcomes in Hepatocellular Carcinoma Treated with Atezolizumab and Bevacizumab: A Propensity Score-matched Analysis

  Yuan-Hung Kuo, Wei Teng, Yen-Hao Chen, Po-Ting Lin, Tsung-Han Wu, Chung-Wei Su, Wei-Ting Chen, Chen-Chun Lin, Chao-Hung Hung, Sheng-Nan Lu, Shi-Ming Lin, Jing-Houng Wang, Chun-Yen Lin

  
• Centromere Protein I, a Cell Cycle Checkpoint Gene, Accelerates Tumor Progression via the Hippo Pathway and Mediates Immune Escape in Hepatocellular Carcinoma

  Risheng He, Yi Xu, Pengbo Zhang, Liang Yu, Jian Ma, Yunfu Cui

  

• PDK4 Regulates Inflammatory Injury in Acute-on-chronic Liver Failure by Phosphorylating STAT1-mediated M1 Polarization of Macrophages

  Shilong Dong, Luyuan Ma, Chuan Shen, Ruolan Gu, Xinyang Li, Ying Xiao, Caiyan Zhao

  

• Fecal Microbiome and Bile Acid Profiles Differ in Preterm Infants with Parenteral Nutrition-associated Cholestasis

  Ellen S. Wagner, Kaitlyn Oliphant, Mark D’Souza, Wilfredo Cruz-Ayala, Ruba K. Azzam, Bree Andrews, Erika C. Claud

  

Review Article

• Applications of Artificial Intelligence and Smart Devices in Metabolic Dysfunction-associated Steatotic Liver Disease

  Wenfeng Zhu, Qi Zheng, Xinyi Xu, Xia Yu, Xianbin Xu, Huilan Tu, Yue Yu, Wubing Ying, Jiahao Xie, Guoping Sheng, Jifang Sheng

  
• Current and Emerging Issues in Familial Hypobetalipoproteinemia-related Steatotic Liver Diseases

  Tian-Wen Lou, Tian-Yi Ren, Jian-Gao Fan

  
• Protein Induced by Vitamin K Absence or Antagonist II in Primary Liver Cancer: Basic Research Insights and Clinical Applications

  Xin Zhang, Rong Wang, Bin Niu, Liaoyun Zhang

  
• Quality and Quantity? The Clinical Significance of Myosteatosis in Various Liver Diseases: A Narrative Review

  Jie Yang, Qing Liu, Chao Sun

  
• Nutrient-stimulated Hormone-based Therapies: A New Frontier in the Prevention and Management of MASH-associated Hepatocellular Carcinoma

  Richard Phillips, Yuk Ting Ma, Wasim Hanif, Tahir Shah, Shivan Sivakumar

  
• ATP-binding Cassette Transporter Defects and Their Roles in Hepatic Diseases

  Danzhu Zhao, George Y. Wu

  

Illuminating and Instructive Clinical Case

• Human Albumin-enriched Peritoneal Dialysis: A Novel Approach to Manage Refractory Ascites and Kidney Dysfunction in Decompensated Advanced Chronic Liver Disease

  Mario Romeo, Silvio Borrelli, Marcello Dallio, Carlo Garofalo, Fiammetta Di Nardo, Paolo Vaia, Carmine Napolitano, Luca De Nicola, Alessandro Federico

  

Research Letter

• Longitudinal Profile of HBsAg Isoforms and Circulating Immune Complexes in the Natural History of Chronic Hepatitis B Infection

  Lung-Yi Mak, Mark Anderson, Tiffany Fortney, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen

  
• Hepatitis C Patient Education: Large Language Models Show Promise in Disseminating Guidelines

  Jinyan Chen, Ruijie Zhao, Chiyu He, Huigang Li, Yajie You, Zuyuan Lin, Ze Xiang, Jianyong Zhuo, Wei Shen, Zhihang Hu, Shusen Zheng, Xiao Xu, Di Lu

  
• Screening for Mutations Causing ACOX2 Deficiency-associated Hypertransaminasemia in Patients with Cryptogenic Liver Injury

  Elisa Herraez, Maria J. Monte, Marta Alonso-Peña, Jesus Prieto, Luis Bujanda, Milagros Muñoz-Chimeno, Ana Avellon, Jose J.G. Marin

  

Consensus

• Expert Consensus on Clinical Applications of Fecal Microbiota Transplantation for Chronic Liver Disease (2025 edition)

  Yongjian Zhou, Li Yang, Yuemin Nan, Liver Related Digestive Diseases Group, Chinese Society of Hepatology, Chinese Medical Association