- Research proposal
- OPEN ACCESS
-
Clinical study on the treatment of acute pancreatitis with external application of Yi-Dan Therapy based on the method of "stagnation requiring dispersion": study protocol for a randomized controlled trial
-
Pei-Xin Ge1,
-
Bo-Yi Jia2,
-
Nai-Wei Zhan2,
-
Li-Bao An2,
-
Qiao-Yan Zhang2,
-
Yan-Mei Cai2,
-
Xiao-Na Zhang2,
-
Shao-Dong Hao2 and
-
Hong-Jie Cheng2,*
Author information
Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100029, China
Department of Gastrointestinal Disease, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing 102488, China
Correspondence to: Hong-Jie Cheng, Department of Gastrointestinal Disease, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing 102488, China. E-mail:
chenghongjie1971@163.com
Abstract
Background
Acute pancreatitis is an unpredictable and potentially lethal disease, causing tremendous pain in patients. The initial treatment of acute pancreatitis in modern medicine is supportive, but it is generally ineffective in relieving abdominal pain and distension. Traditional Chinese medicine has been shown to be more effective in regulating the body's homeostasis and reducing the clinical symptoms of pancreatitis. Yi-Dan ointment, derived from Dahuang-Mudan Decoction, is an effective external ointment for treating acute pancreatitis. The aim of this trial is to investigate the clinical efficacy of Yi-Dan ointment, providing a valuable complement to existing treatment options for pancreatitis.
Methods
This is a randomized controlled clinical trial with two parallel groups. Patients in the control group were given basic treatment and nursing for 7 days; in the treatment group, Yi-Dan ointment was applied externally in addition to basic treatment and nursing. The main indicator is the overall efficacy, serum amylase, acute physiology and chronic health evaluation â
¡ score, symptom score, inflammatory markers, and classification of computed tomography.
Conclusion
The trial results will provide high-quality evidence for Yi-Dan ointment, and provide a complement to existing treatment options for pancreatitis.
Keywords
acute pancreatitis,
traditional Chinese medicine,
external treatment,
Yi-Dan ointment,
randomized controlled trial
|
Copyright © 2025 Authors.
This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 License (CC BY-NC 4.0), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
|
About this Article
Cite this article
|
Ge PX, Jia BY, Zhan NW, An LB, Zhang QY, Cai YM, et al. Clinical study on the treatment of acute pancreatitis with external application of Yi-Dan Therapy based on the method of "stagnation requiring dispersion": study protocol for a randomized controlled trial. Gastroenterol & Hepatol Res. 2024;6(2):6. doi: 10.53388/ghr2024006.
|
| Copied to clipboard
|
Copy
Export to RIS
Export to EndNote
|
|
Citation copied!
|
Article History
| Received |
Revised |
Accepted |
Published |
|
|
|
|
June 30, 2024
|
DOI
http://dx.doi.org/10.53388/ghr2024006
-
Gastroenterology & Hepatology Research
-
-
eISSN 2703-173X