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Epigenetic modification of the Wnt signaling pathway: a potential target for intestinal aging

Ji-Da Wang^1,#,
Yue-Xuan Shi^1,#,
Ogbe Susan Enechojo^1,2,
Huan-Tian Cui³,
Ying Wang¹,
Abankwah Joseph Kofi¹,
Xiang-Ling Wang¹,
Yu-Bong Bian^1,* and
Xiao-Qian Chu^1,*

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Gastroenterology & Hepatology Research 2024;6(2):8

doi: 10.53388/ghr2024008

Abstract

The world has entered an aging society, and it is expected that the global population aged 60 years or older will reach 1.5 billion by 2035. Aging is gradually becoming a major public health issue, posing a significant challenge to healthcare systems. It is a complex natural physiological process involving the irreversible degeneration of body cells, tissues, and organs, and it is a major risk factor for many chronic diseases.

Keywords

Wnt signaling pathway, intestinal aging, intestinal stem cells

Copyright © 2025 Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 License (CC BY-NC 4.0), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang JD, Shi YX, Enechojo OS, Cui HT, Wang Y, Kofi AJ, et al. Epigenetic modification of the Wnt signaling pathway: a potential target for intestinal aging. Gastroenterol & Hepatol Res. 2024;6(2):8. doi: 10.53388/ghr2024008.

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Article History

Received	Revised	Accepted	Published
			June 30, 2024

DOI http://dx.doi.org/10.53388/ghr2024008

Gastroenterology & Hepatology Research
eISSN 2703-173X

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