Objective
To observe the clinical efficacy of Jiawei Lizhong Tang combined with dorsal Yu acupoint embedding in patients with non-alcoholic steatohepatitis (NASH).
Methods
A total of 118 patients with NASH who attended the Department of Gastroenterology at Liuzhou Hospital of Traditional Chinese Medicine from January 2020 to December 2022 were selected as study subjects. The participants were randomly assigned to either the control group or the observation group using a random number table, with 59 cases in each group. The control group received treatment with Western medicine (compound glycyrrhizin capsule), whereas the observation group received treatment with traditional Chinese medicine combined with thread embedding (Jiawei Lizhong Tang combined with dorsal Yu acupoints embedding). Both groups received a treatment course of 12 weeks. The following anthropometric indicators were measured: weight, waist circumference, and body mass index. Liver function was assessed by measuring alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), and total bilirubin (TBIL). Lipid profile indicators included triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Blood glucose indicators included fasting blood glucose, fasting insulin (FINS), and insulin resistance index (HOMA-IR). Additionally, liver stiffness measurement (LSM), controlled attenuation parameter (CAP), and liver/spleen CT ratio were assessed. Clinical efficacy was evaluated at the end of the treatment period.
Results
After 12 weeks of treatment, significant improvements were observed in weight, waist circumference, BMI, serum ALT, AST, GGT, TBil, TG, TC, LDL-C, HDL-C, fasting glucose, FINS, HOMA-IR, LSM, CAP, and liver/spleen CT ratio in both groups compared to baseline (Pï¼0.05). The improvements in these indicators were significantly better in the observation group than in the control group after treatment (Pï¼0.05).
Conclusion
The treatment of NASH with Jiawei Lizhong Tang combined with dorsal Yu acupoint embedding effectively improves patient condition, reduces liver function damage, regulates blood lipids, insulin resistance, and hepatic steatosis. The therapeutic effect is superior to that of Western medicine therapy.