Original Article

Comparative Efficacy of Promising Targets in the Treatment of Metabolic Dysfunction-associated Steatotic Liver Disease and Steatohepatitis: A Systematic Review and Network Meta-analysis Wenjing Ni, Jie Li, Xue Bai, Sisi Zhou, Xiangyu Wu, Leyao Jia, Zhuoru Jiang, Jiali Wu, Ming Li, Connie Wong, Chao Wu, Junping Shi, Mindie H. Nguyen Published online: July 20, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00596

Referral-spectrum Effect in Hypercupriuric Referrals for Suspected Wilson Disease: Diagnostic Implications for Ceruloplasmin and 24-hour Urinary Copper Excretion Yu Zhang, Yijun Bao, Yiting Wang, Yulin Tao, Ruijia Li, Hongli Liu, Li Wang, Tianhao Mao, Wenjing Ji, Yuxiang Gong, Siwei Zheng, Kai Zhang, Xing Liu, Shasha Li, Yongfeng Yang Published online: July 2, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00294

Berberine Attenuates Hepatic Sinusoidal Obstruction Syndrome by Inhibiting Endothelial-mediated Neutrophil Recruitment and Activation Yiken Lin, Wenjia Tian, Weiming Dai, Ning Chen, Huifeng Hao, Yulan Liu Published online: July 20, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00024

Baseline Liver Fibrosis Severity Predicts Superior HBeAg Clearance and Fibrosis Reversal following Peg-IFNα plus Nucleos(t)ide Analog Therapy in HBeAg-positive Chronic Hepatitis B Patients Yaqin Zhang, Fengxin Chen, Shuojie Wang, Xin Wei, Shiyu Wang, Linmei Yao, Zixuan Gao, Wen Deng, Minghui Li Published online: July 9, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00093

Evaluation of the Safety and Efficacy of SOF/VEL Treatment and Pre-treatment of TAF in Patients with Chronic Hepatitis B Virus/Hepatitis C Virus Coinfection: A Multicenter Study Yifan Han, Ning Lin, Dazhi Zhang, Zuxiong Huang, Minghua Su, Jiawei Geng, Zhili Wen, Songsong Xie, Xiaobo Lu, Hong You, Liting Zhang, Jia Shang, Liaoyun Zhang, Yuemin Nan, Biao Wu, Chengzhen Lu, Ying’an Jiang, Qian Kang, Hongyu Chen, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu Published online: May 29, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00168

Review Article

The Role of Nitric Oxide in Chronic Liver Disease: A Review Danzhu Zhao, George Y. Wu Published online: July 2, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00173

Mineralocorticoid Receptor Antagonists for Liver Fibrosis: Potential Mechanisms and Research Progress Huaijun Zheng, Ye Feng Published online: June 26, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00019

Advances in Lipid Metabolism Reprogramming in Hepatocellular Carcinoma Weiqi Duan, Qian Jian, Bo Sun, Hong Yang, Youcai Deng, Yu Peng, Sulai Liu Published online: June 26, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00055

Advances in Precise Assessment of Portal Pressure in Porto-sinusoidal Vascular Disease Kun Zhu, Qingchun Fu, Muyun Liu Published online: June 26, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00334

Research Letter

qHBsAg Trajectories with Peg-IFNα-2b Add-on Therapy in Nucleos(t)ide Analog-experienced HBeAg-positive Chronic Hepatitis B Kezhen Hu, Yanzhen Bi, Xiaoying Li, Xiangzhong Liu, Haoxi Wang, Yong Zhou, Yongning Xin Published online: July 24, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00175

FN1 Knockout Inhibits Tumorigenesis but Promotes Lung Metastasis in Hepatocellular Carcinoma Meng Han, Xin Liu, Jian-Jun Gou, Feng-Min Lu Published online: July 2, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2025.00689

Letter to the Editor

Expanding the Horizon: A Roadmap for Artificial Intelligence Integration in Metabolic Dysfunction-associated Steatotic Liver Disease Abdulrahman Ismaiel, Stefan-Lucian Popa Published online: June 26, 2026 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2026.00266 VIEW RELATED CONTENT : Applications of Artificial Intelligence and Smart Devices in Metabolic Dysfunction-associated Steatotic Liver Disease Wenfeng Zhu, Qi Zheng, Xinyi Xu, Xia Yu, Xianbin Xu, Huilan Tu, Yue Yu, Wubing Ying, Jiahao Xie, Guoping Sheng, Jifang Sheng