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Online First Articles

The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Infectious Hepatitis

Pegylated Interferon-based Treatment Improves Response Rates in Immune-tolerant Patients with Chronic Hepatitis B: A Prospective Trial

Min Liu, Lili Zuo, Yuting Zhang, Bing Bu, An Xiao, Ling Zhu, Xiuying Ma, Yilan Wang, Wei Yue, Jiawei Geng, Xueshan Xia

Published online: March 31, 2026

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doi:10.14218/JCTH.2025.00712

Liver Transplantation and Surgery

Galectin-3 Promotes Graft Injury via NLRP3 Pyroptosis in Steatotic Liver Transplantation: A Therapeutic Target for Donor Optimization

Xianwu Yang, Shirui Huang, Ruisi Ma, Zhihui Zhu, Yingquan Zhuo, Jiafei Yang, Jun Du, Huajian Gu

Published online: March 24, 2026

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doi:10.14218/JCTH.2025.00561

Hepatic and Biliary Neoplasia

Neu5Gc-associated Serum Immunoglobulin G Glycosylation as a Diagnostic Biomarker for Hepatocellular Carcinoma

Xu Cao, Xiwei Lu, Qingwei Li, Jiali Lu, Xiaoping Song, Yinglun Han, Chunwen Pu, Yue Pang

Published online: March 20, 2026

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doi:10.14218/JCTH.2025.00654

Liver Injury, Autoimmune, and Cholestatic Diseases

A Multi-omics and Machine Learning Framework Identifies Plasma SBDS as a Causal Biomarker and Therapeutic Target in Primary Sclerosing Cholangitis

Pengfei Cheng, Yuanming Qiang, Yibo Sun, Binwei Duan, Yabo Ouyang, Guangming Li

Published online: March 20, 2026

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doi:10.14218/JCTH.2025.00676

Review Article

Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure

Hong Zhou, Hong Wu, Shao-Hui Su, Shan-Hong Tang

Published online: March 18, 2026

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doi:10.14218/JCTH.2025.00657

Congenital Portosystemic Shunts – A Review

George Y. Wu

Published online: February 4, 2026

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doi:10.14218/JCTH.2025.00090

Research Letter

Analysis of Protein Binding to Liver Mitochondria by Horizontal Polyacrylamide Gel Electrophoresis Using a Converted Agarose Electrophoresis Unit

Bianca Thakkar, George Y. Wu

Published online: February 27, 2026

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doi:10.14218/JCTH.2025.00651