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Online First Articles

The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Liver Transplantation and Surgery

Serum miR-381-3p: Diagnostic Role and Mechanisms in Liver Transplant Ischemia-reperfusion Injury

Xiaobin Chi, Zerun Lin, Zhijian Chen, Jianda Yu, Yongbiao Chen, Honghuan Lin, Qiucheng Cai, Lizhi Lv

Published online: February 5, 2026

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doi:10.14218/JCTH.2025.00571

Infectious Hepatitis

Association of Changes in Portal Insulin with Immunometabolism During and After Hepatitis C Virus Infection

Matthew G. Menkart, Jenna L. Oringher, Moumita Chakraborty, James A. Haddad, Gabriella M. Quinn, Grace Zhang, Elizabeth C. Townsend, Kareen L. Akiva, Lisa Scheuing, Anjali Rai, Shakuntala Rampertaap, Sergio D. Rosenzweig, Christopher Koh, Rebecca J Brown, Regina Umarova, Elliot B. Levy, David E. Kleiner, Rabab O. Ali, Ohad Etzion, Rownock Afruza, Theo Heller

Published online: February 4, 2026

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doi:10.14218/JCTH.2025.00498

Eight-year Results from Two Randomized Phase 3 Trials of Tenofovir Alafenamide for Chronic Hepatitis B Virus Infection in China

Jinlin Hou, Qin Ning, Zhongping Duan, Yu Chen, Qing Xie, Lunli Zhang, Shanming Wu, Hong Tang, Jun Li, Feng Lin, Yongfeng Yang, Guozhong Gong, Yanwen Luo, Yan Chen, Frida Abramov, Leland J. Yee, Hongyuan Wang, Roberto Mateo, Tahmineh Yazdi, Irina Botros, Chengwei Chen, Yan Huang, Mingxiang Zhang, Jidong Jia

Published online: February 4, 2026

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doi:10.14218/JCTH.2025.00438

Traditional and Novel Virologic Markers for Functional Cure and HBeAg Loss with Pegylated Interferon in Chronic Hepatitis B: A Systematic Review and Meta-analysis

Ying Zhang, Long-Fei Wang, Jing Chen, Mindie H. Nguyen, Qi Zheng

Published online: December 26, 2025

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doi:10.14218/JCTH.2025.00443

Metabolic Liver Diseases

Intestinal Candida albicans is Associated with Subclinical Coronary Atherosclerosis in Metabolic Dysfunction-associated Steatotic Liver Disease with Cirrhosis

Nantawat Satthawiwat, Suthida Visedthorn, Pakorn Ruengket, Prangwalai Chanchaem, Pattida Kongsomboonchoke, Monravee Tumkosit, Pairoj Chattranukulchai, Sunchai Payungporn, Pisit Tangkijvanich

Published online: January 27, 2026

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doi:10.14218/JCTH.2025.00507

Metabolic Risk Factors and Clinical Presentations of Metabolic Dysfunction-associated Steatotic Liver Disease Using Data from the All of Us Research Program

Ke-Qin Hu, Seyedeh Neelufar Payrovnaziri, Argyrios Ziogas, Steven Hiek, Kuangda Shan, Tevan Luong, Jenny Fang, Hoda Anton-Culver

Published online: January 27, 2026

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doi:10.14218/JCTH.2025.00393

Bidirectional Regulation between Metabolic Dysfunction-associated Steatotic Liver Disease and Sarcopenia via Liver-muscle Crosstalk

Yeyu Song, Yameng Liu, Jie Jiang, Youjie Zheng, Zixuan Wang, Cen Xie, Jian-Gao Fan

Published online: January 7, 2026

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doi:10.14218/JCTH.2025.00538

Liver Failure, Cirrhosis and Portal Hypertension

Cathepsin K Alleviates Liver Fibrosis by Inhibiting the TGF-β/Smad Signaling Pathway and Inducing Hepatic Stellate Cell Apoptosis

Zhandong Lin, Yue Shi, Mengjiao Sun, Jiawei Cui, Dandan Zhao, Yaoyao Mao, Congyue Zhang, Ying Zhang, Qianqian Zheng, Yukai Chen, Shaoya Li, Yuemin Nan

Published online: January 22, 2026

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doi:10.14218/JCTH.2025.00592

Hepatic and Biliary Neoplasia

Prognostic Nutritional Index Predicts Outcomes in Hepatocellular Carcinoma Treated with Atezolizumab and Bevacizumab: A Propensity Score-matched Analysis

Yuan-Hung Kuo, Wei Teng, Yen-Hao Chen, Po-Ting Lin, Tsung-Han Wu, Chung-Wei Su, Wei-Ting Chen, Chen-Chun Lin, Chao-Hung Hung, Sheng-Nan Lu, Shi-Ming Lin, Jing-Houng Wang, Chun-Yen Lin

Published online: December 8, 2025