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Online First Articles

The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Infectious Hepatitis

Chronic Hepatitis B in the Asia-Pacific Region: Results of the 2023 Global Burden of Disease Study

Zhengzhao Lu, Dong Xu, Wei Ji, Jingjie Zhao, Tingting Xiao, Dongxu Wang, Yuanyuan Kong, Jidong Jia, Hong You, Xinyu Zhao

Published online: June 26, 2026

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doi:10.14218/JCTH.2026.00114

Evaluation of the Safety and Efficacy of SOF/VEL Treatment and Pre-treatment of TAF in Patients with Chronic Hepatitis B Virus/Hepatitis C Virus Coinfection: A Multicenter Study

Yifan Han, Ning Lin, Dazhi Zhang, Zuxiong Huang, Minghua Su, Jiawei Geng, Zhili Wen, Songsong Xie, Xiaobo Lu, Hong You, Liting Zhang, Jia Shang, Liaoyun Zhang, Yuemin Nan, Biao Wu, Chengzhen Lu, Ying’an Jiang, Qian Kang, Hongyu Chen, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu

Published online: May 29, 2026

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doi:10.14218/JCTH.2026.00168

Metabolic Liver Diseases

Regional Inequities in Metabolic Dysfunction–associated Steatotic Liver Disease Burden and Care Quality in High-burden Settings: Implications for Health Systems

Kexin Zhang, Chengxia Kan, Sufang Sheng, Wei Xu, Fang Han, Jian Chen, Xuan Li, Ningning Hou, Ying Xue, Xiaodong Sun

Published online: June 22, 2026

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doi:10.14218/JCTH.2026.00127

Hepatic and Biliary Neoplasia

Targeting the 4EBP1/HSP90β/Nrf2 Axis Sensitizes β-catenin-mutant Hepatocellular Carcinoma to mTOR Inhibitors via Ferroptosis Induction

Rong Li, Yi Zhou, Zimu Wang, Gang Liu, Deyu Fan, Lanxuan Huang, Fule Deng, Ning Wei, Runze Shang, Meng Xu

Published online: June 16, 2026

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doi:10.14218/JCTH.2026.00072

Liver Failure, Cirrhosis and Portal Hypertension

GSTM3 Knockdown Promotes Liver Fibrosis Reversal by Inhibiting Hepatic Stellate Cell Activation via PPARγ Signaling

Chenxue Hou, Bingqing Yang, Yuanying Zhao, Hao Chang, Tong Bu, Qi Wang, Yue Li

Published online: May 25, 2026

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doi:10.14218/JCTH.2025.00658

Liver Injury, Autoimmune, and Cholestatic Diseases

A Dual Time Window-driven Strategy to Optimize Primary Biliary Cholangitis Treatment via Alkaline Phosphatase Normalization

Han Zhao, Yansheng Liu, Yingmei Tang, Ningning Wang, Yanmin Liu, Yiling Li, Chunyang Huang, Jieting Duan, Yan Feng, Linhua Zheng, Ruiqing Sun, Xiufang Wang, Juan Deng, Gui Jia, Patrick S.C. Leung, M. Eric Gershwin, Yulong Shang, Ying Han

Published online: May 15, 2026