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Online First Articles

The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Liver Failure, Cirrhosis and Portal Hypertension

A Novel Simplified Prognostic Model for 90-day Transplant-free Survival in Patients with Severe Acute Liver Injury/Acute Liver Failure

Yan Ren, Manman Xu, Wenling Wang, Ming Kong, Yu Chen

Published online: April 28, 2026

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doi:10.14218/JCTH.2026.00075

Liver Injury, Autoimmune, and Cholestatic Diseases

Bile Drainage Improves Survival in Amatoxin-induced Severe Liver Injury: A Prospective Pilot Cohort Study

Xiuying Ma, Bin Han, Wei Yue, Yuan Shen, Jiawei Geng

Published online: April 27, 2026

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doi:10.14218/JCTH.2026.00057

A Multi-omics and Machine Learning Framework Identifies Plasma SBDS as a Causal Biomarker and Therapeutic Target in Primary Sclerosing Cholangitis

Pengfei Cheng, Yuanming Qiang, Yibo Sun, Binwei Duan, Yabo Ouyang, Guangming Li

Published online: March 20, 2026

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doi:10.14218/JCTH.2025.00676

Review Article

Short-chain Fatty Acids and Bile Acids Signaling in Chronic Hepatitis B

Siqi Sun, Sisi Yang, Yihe Yu, Jiyang Chen, Jintao Ning, Yida Yang, Hongyu Jia

Published online: April 28, 2026

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doi:10.14218/JCTH.2026.00118

The Association of Alpha-1 Antitrypsin Deficiency and Arterial Aneurysms: An Update and Review

Moana Da Silva Santiago, George Y. Wu

Published online: April 27, 2026

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doi:10.14218/JCTH.2026.00043

The Multifaceted Roles of Gut Microbiota and Their Metabolites in Metabolic Dysfunction-associated Steatotic Liver Disease: A Literature Review

Yunqi Zhang, Dengqin Wang, Bo Zhuang, Fangzhuo Zhu, Chengwei Tan, Jing Zhang, Qianqian Zhang

Published online: April 24, 2026

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doi:10.14218/JCTH.2025.00605

Dubin-Johnson and Rotor Syndromes: A Review and Update of Pathophysiological Mechanisms

Bianca Thakkar, George Y. Wu

Published online: April 9, 2026

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doi:10.14218/JCTH.2025.00560

Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure

Hong Zhou, Hong Wu, Shao-Hui Su, Shan-Hong Tang

Published online: March 18, 2026

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doi:10.14218/JCTH.2025.00657

Letter to the Editor

Letter to the Editor: Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study

Chenhao Ye, Lei Wang

Published online: April 27, 2026

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doi:10.14218/JCTH.2026.00159

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