Cathepsin K Alleviates Liver Fibrosis by Inhibiting the TGF-β/Smad Signaling Pathway and Inducing Hepatic Stellate Cell Apoptosis
Zhandong Lin, Yue Shi, Mengjiao Sun, Jiawei Cui, Dandan Zhao, Yaoyao Mao, Congyue Zhang, Ying Zhang, Qianqian Zheng, Yukai Chen, Shaoya Li, Yuemin Nan
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[ PDF ] 187-201
doi:10.14218/JCTH.2025.00592
Repurposing SGLT2 Inhibitors for Cirrhotic Ascites: From Mechanistic Research to Clinical Exploration
Yuan Gao, Yunyi Gao, Dong Ji, Zhongjie Hu
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[ PDF ] 232-239
doi:10.14218/JCTH.2025.00465
Tumor Vaccines in Hepatocellular Carcinoma: Advances, Challenges, and the Path Toward Precision Immunotherapy
Bin Niu, Jun Xu, Liaoyun Zhang
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[ PDF ] 202-214
doi:10.14218/JCTH.2025.00401
Immune Checkpoint Inhibitor–induced Liver Injury: A Critical Appraisal of Treatment and Rechallenge Controversies
Fernando Bessone, Nelia Hernandez
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[ PDF ] 240-244
doi:10.14218/JCTH.2025.00450
Extrahepatic Autoimmune Diseases in Autoimmune Hepatitis: Their Prevalence, Predictors, and Influence on Early Treatment Outcomes
Yue-Yang Ma, Wei-Hao Zhao, Ke-Ying Ou, Jia-Nan Cui, Chuan-Su Yuan, Bin Liu, Yong-Feng Yang, Qing-Fang Xiong
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[ PDF ] 23-30
doi:10.14218/JCTH.2025.00424
Primary Biliary Cholangitis–associated Osteoporosis: Contemporary Review of Pathogenesis and Management
Jiaqi Yang, Shuhao Su, Ting Yuan, Caiyun Yang, Jie Luo, Xingchen Liu, Guanya Guo, Changcun Guo, Ying Han
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[ PDF ] 76-82
doi:10.14218/JCTH.2025.00505
Chinese Guidelines for Clinical Diagnosis, Treatment, and Management of Cirrhosis (2025)
Xiaoyuan Xu, Huiguo Ding, Hong You, Yujuan Guan, Jinghang Xu, Wengang Li, Ying Han, Yaping Wang, Yifan Han, Jidong Jia, Lai Wei, Zhongping Duan, Yuemin Nan, Hui Zhuang, Chinese Society of Hepatology, Chinese Medical Association
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[ PDF ] 96-115
doi:10.14218/JCTH.2025.00517
Bidirectional Regulation between Metabolic Dysfunction-associated Steatotic Liver Disease and Sarcopenia via Liver-muscle Crosstalk
Yeyu Song, Yameng Liu, Jie Jiang, Youjie Zheng, Zixuan Wang, Cen Xie, Jian-Gao Fan
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[ PDF ] 121-136
doi:10.14218/JCTH.2025.00538
Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study
Lexin Liu, Qiumiao Xu, Shanshan Lin, Zehui Wei, Guoxin Huang
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[ PDF ] 39-49
doi:10.14218/JCTH.2025.00533
Serum Interleukin-8 for Differentiating Invasive Pulmonary Aspergillosis from Bacterial Pneumonia in Patients with HBV-Associated Acute-on-Chronic Liver Failure
Lanyue Huang, Yuzhao Feng, Wei Wang, Wei Liu, Yunhui Liu, Liang Chen, Yuxin Niu, Tingting Liu, Mi Song, Yiwei Xu, Zhongyuan Yang, Guang Chen, Qin Ning, Tao Chen, Lin Zhu
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[ PDF ] 31-38
doi:10.14218/JCTH.2025.00645
Expert Consensus on the Diagnosis and Management of Inherited Hyperbilirubinemia (2025)
Sujun Zheng, Xiaoyuan Xu, Yuemin Nan, Wei Hou, Jie Bai, Shan Tang, Chen Liang, Lei Luo, Jianshe Wang, Xinhua Li, Min Zhang, Guohong Deng, Hui Liu, Yongfeng Yang, Wen Xie, Xiaojuan Ou, Xinxin Zhang, Lai Wei, Jidong Jia, Zhongping Duan, Inherited Metabolic Liver Disease Collaboration Group, Chinese Society of Hepatology, Chinese Medical Association
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[ PDF ] 83-95
doi:10.14218/JCTH.2025.00440
Traditional and Novel Virologic Markers for Functional Cure and HBeAg Loss with Pegylated Interferon in Chronic Hepatitis B: A Systematic Review and Meta-analysis
Ying Zhang, Long-Fei Wang, Jing Chen, Mindie H. Nguyen, Qi Zheng
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[ PDF ] 159-167
doi:10.14218/JCTH.2025.00443