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FTO Promotes Hepatocellular Carcinoma Progression by Mediating m6A Modification of BUB1 and Targeting TGF-βR1 to Activate the TGF-β Signaling Pathway

Lin Zhang, Li Gan, Yuru Lin, Zhechuan Mei, Shengtao Liao

[ Html ] [ PDF ] 385-394

doi:10.14218/JCTH.2025.00007

Ketamine Hepatotoxicity: An Underappreciated Cause of Liver Damage - Analysis by RUCAM

Bianca Thakkar, George Y. Wu

[ Html ] [ PDF ] 524-531

doi:10.14218/JCTH.2024.00478

Characteristics of a Chinese Cohort of Patients with Chronic Hepatitis C Infection (2019–2023) and a Case Report of Resistance-associated Substitutions to Sofosbuvir-velpatasvir Treatment

Hao Xiong, Shaokun Pan, Chaohui Zhou, Hong Shi, Youhua Xie, Jinsheng Guo

[ Html ] [ PDF ] 605-608

doi:10.14218/JCTH.2025.00033

Key Points and Future Directions from the 2024 Chinese Guidelines for Fatty Liver Disease

Maria Tampaki, Evangelos Cholongitas

[ Html ] [ PDF ] 434-439

doi:10.14218/JCTH.2025.00051

Analysis of the Disease Spectrum Characteristics of Inherited Metabolic Liver Diseases in Two Hepatology Specialist Hospitals in Beijing over the Past 20 Years

Wei Hou, Yuanzhi Huang, Tang Shang, Zheng Wang, Wei Zhang, Kefi Wang, Yinjie Gao, Min Zhang, Sujun Zheng

[ Html ] [ PDF ] 367-373

doi:10.14218/JCTH.2025.00030

Non-variceal Extrahepatic Portosystemic Shunts: A Review of Pathogenesis, Diagnosis, and Treatment

Nicole M. Anastasio, George Y. Wu

[ Html ] [ PDF ] 425-433

doi:10.14218/JCTH.2024.00315

Investigation of HO-1 Regulation of Liver Fibrosis Related to Nonalcoholic Fatty Liver Disease Through the SIRT1/TGF-ß/Smad3 Pathway

Mengjiao Sun, Xiaoqing Wu, Zhandong Lin, Congyue Zhang, Jiawei Cui, Yaoyao Mao, Yue Shi, Jiaming Zhang, Yuemin Nan

[ Html ] [ PDF ] 456-468

doi:10.14218/JCTH.2024.00481

Intestinal Depletion of TM6SF2 Exacerbates High-fat Diet-induced Metabolic Dysfunction-associated Steatotic Liver Disease through the Gut-liver Axis

Li-Zhen Chen, Yu-Rong Wang, Zhen-Zhen Zhao, Shou-Lin Zhao, Cong-Cong Min, Yong-Ning Xin

[ Html ] [ PDF ] 443-455

doi:10.14218/JCTH.2024.00407

Improved Discrimination and Predictive Ability of Novel Prognostic Scores for Long-term Mortality in Hospitalized Patients with Cirrhosis

Sipu Wang, Gaoyue Guo, Han Wang, Xuqian Zhang, Wanting Yang, Jie Yang, Liping Wu, Chao Sun

[ Html ] [ PDF ] 484-492

doi:10.14218/JCTH.2025.00004

Ursolic Acid Modulates Estrogen Conversion to Relieve Inflammation in Metabolic Dysfunction-associated Steatotic Liver Disease via HSD17B14

Simin Gu, Hui Zhang, Zhekun Xiong, Chong Chen, Junmin Wang, Dan Fang, Yiyuan Zheng, Yong Li

[ Html ] [ PDF ] 269-277

doi:10.14218/JCTH.2024.00414

Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Hepatitis B: Protocol for a Phase 3 Randomized Trial

Xiaobo Cai, Yin Qu, Wen Xie, Yanbin Wang, Mengyu Zhao, Ling Zhang, Ying Luo, Ping Yin, Jun Cheng, Lungen Lu

[ Html ] [ PDF ] 361-366

doi:10.14218/JCTH.2024.00472

Inhibition of Cyclooxygenase-2 Upregulates the Nuclear Factor Erythroid 2-related Factor 2 Signaling Pathway to Mitigate Hepatocyte Ferroptosis in Chronic Liver Injury

Zhu Yang, Yang Tai, Tian Lan, Chong Zhao, Jin-Hang Gao, Cheng-Wei Tang, Huan Tong

[ Html ] [ PDF ] 409-417

doi:10.14218/JCTH.2024.00440

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